I want to give a couple of thoughts before I give my predictions.
Phillies: I have the Phils in a franchise league we're keep tabs of minor leaguers and the like, so I'm sort of versus in their farm system. They don't have much right now with Halladay and Lee trades. They have one of the best rotations of all time, that could rival the likes of Smoltz, Maddux, Glavine, and Avery in the 90's.
The big caveat to the Phillies is their bench. If Howard, Utley, Rollins, or Victorino get hurt, it's going to be really hard to replace them. Their bench is an abomination in comparison to their pitching depth. I think Tagg Bozied (who is a story in himself) has a good shot as the bench player to backup 3rd and first. Outside of that it's Russ Gload and Wilson Valdez to handled the backups... not exactly good replacements. Non roster invitees to note are Delwyn Young and Brandon Moss.
In theory, Dominic Brown should be as good if not better then Werth, but he's got to live up to the type.
They should still win the NL East, but it could easily come falling off the tracks due to their offense.
O's: Their lineup should be really good this year, and should surprise some teams. Nolan Reimold pretty much will need to rot in the minors because Vladdy will be DH moving Scott to LF putting Pie to the bench. Kevin Gregg is adequate at closing games, but as all of us Cubs fan know, he's not a sure fire thing. The O's rotation is still wayyyyy young and have no veteran leader (because it's sure not Jeremry Guthrie). Duchscherer could be that person, but I don't think he's got enough time as an Ace to do that. With how competitive the AL East is, I just don't see them getting out of the cellar.
AL:
EAST: BoSox
CENT: Minn
WEST: Texas
WC: NYY/TBR/LAA (too hard for me too honestly pick this one). The yanks rotation is horrible, the rays shipped off so much and are relying on young players/pitchers too much, the Angels have seemed to put a fairly decent team together this year.
NL:
EAST: Phils
CENT: Reds
WEST: SF
WC: Milwaukee
WS: BoSox over Philly