Rivera in Carolina and Fisher in St. Louis both lined up in 46 formations more than a little, and it was still pretty effective in today's NFL as both the Rams and Panthers had very good to excellent D at times during the season.
Th '85 Bears talent made the philosophy work. I read the comments here and was a little surprised that many seem to think the 46 was only about sacks, it was also INCREDIBLY hard to run against and the confusion it caused for QBs like Montana, Theismann, Simms et al. in '85 was a testament to the value of making your opponent one dimensional and then teeing off on them. Wilson and Marshall would still be Pro-Bowlers today. Singletary, Hampton, Dent would still be Hall of Fame caliber and the rest of that defense would be equal to or better than many NFL players starting the league today - Richardson was always under-rated at CB and McMichael was an outstanding DT, as was Perry until he got too fat and happy.
Now, the one thing I would say is that the hit Marshall put on Ferguson would probably draw a 3 game suspension in the pussified NFL of today...