Dropbacks - No longer will every snap look the same. Quarterbacks are getting 7-step drops, 5-step drops and so on. EA doesn't want you holding down on the stick to try and get away from the line -- let the QB do his job.
Trajectories - Remember last year when you'd throw a screen pass and the ball would arc in the air just long enough for the defender to screw everything up? Tiburon's created 25 trajectories to get the ball to the receiver in the most appropriate way. This means shovel passes, dumps and so on. Sure, you could always choose between a bullet or a lob in Madden NFL 12, but the trajectory of the ball was always the same. Not anymore.
QB Avoidance Moves - You're going to move slower in the pocket this time around -- at least when looking to pass -- but now you have the eight directions of the right stick to move your quarterback. These little stab moves buy you time to get free and make the play.
Receiver Awareness - All those times when you'd complete a pass well before the receiver completed his route? You're not going to be doing those as much if EA has its way. This year, the icons over receivers will light up when a player is expecting a pass. This doesn't mean he's open. This just means the receiver is looking for the ball. Similarly, you can throw when the icon isn't lit up, but the chances of a catch are lower.
Read & React Defense - The days of the blind swat are over. To make a play, the defender is going to have to have his eyes on the ball. Also, coverage is going to be disguised this year. If the offense sends a man in motion, zone coverage is going to send a man, too, so as not to tip its hand.