Here
It's basically about a virus that wipes out the entire male population on Earth... except for this one dude Yorick and his pet monkey Ampersand. The women break out into a whole bunch of different factions: a new "amazon" man-haters, the politician's wives that take over their dead husbands roles, some Israeli commandos... all having their own agendas while Yorick is just looking for his girlfriend.
Thats an interesting scenario. It could be the greatest thing ever to happen to that guy or the worst. His testicles would be the most valuable item on the planet.
Although, a virus is a finicky thing, its not alive, so I am not certain were it airborne, if all the possibly hosts disappeared, would the virus still exist. So repopulating the planet might not be an option, unless the dude could pass on his immunity. Im pretty sure you can generate enough genetic diversity with one male and an assload of females, so it would be unlikely any of his line, would need to have relations with any other member of his seed for quite awhile, and by that time it would probably be rather diluted. I stress "need", because any female offspring he produced, if they wanted to get down on the farm with a man, would have no choice but to get boned by a close relative.
This is actually an interesting scenario, to guestimate how long we could go without in breeding.
lets assume a woman is capable of bearing children for 45 years (guesstimate). So Im sure there are female babies present or pregnat women who havent given birth yet, so Id say we would roughly have at least 45 years where inbreeding isnt required. the key is over that 45 year period, how much could you dilute the males blood line, so when inbreeding must occur you can ensure maximum diversity.
Lets say a male is sexually mature at 15 (varies, guestimate). So we have the first sexually mature male 15 years later so now we have 30 years left on the no inbreeding clock. (im just using the example of one direct line, the dude could probably father over a thousand children a year, hed be busy but its possible)
ok so lets say the 15 year old starts getting busy and his kid is now 15 so that leaves 15 years on the inbreedometer.
he has a kid, so that kids now 15 (omega mans great grandson) and he has to bang whatever non related cougars can bear children
So the first generation that MUST inbreed would be the great great grandchildren of the last man on earth. As long as they can steer clear of inbreeding with the Female portion and male portion of their blood line (which there should be enough children at this point where it isnt an issue) I dont think there would be any ill effects from inbreeding essentially, the great great grandchildren would only be 1/16th the genetic make up of the last man.
It would have to be monitored throughout the whole process though, At no point do you want earlier related generations boning and making babies. once the great great grandchildren are mature, the only people making babies should be great great grandchildren with other great great grandchildren, because any non related women would be too old to have children, and you dont want earlier generations making genetic frankensteins.
So by the time the great grandchildren females are incapable of producing offspring (which ideally, no female offspring of the omega man should have concieved, until the great great grandchildren) there should be a healthy diverse population.