Lonzo certainly makes a huge difference defensively, but he doesn't, and shouldn't, make up the entire defense. There's still ways players like Derozan can be part of a good defensive scheme without being a good individual 1on1 defender.
Not saying stuff like this should be happening every other possession, but just shows you can play good defense now and again while Derozan and Vuc are on the floor. And really I don't see any reason it couldn't happen with Zach in the lineup also. If you look at Troy Brown Jr or Javonte Green, they're not doing anything Zach couldn't do. Really Ayo is doing most of the legwork here.